Neuro-oncology is a very broad clinical and scientific discipline that concerns the diagnostic and therapeutic care of primary tumors of the CNS, neurological complications of cancer, whether tumoral or not, and neuro-oncogenetic pathologies. It is transversal, potentially involving all the structures of the central and peripheral nervous system and requires an interdisciplinary approach.
We are developing at NETRI 3D-Deposition Chamber microfluidic devices coupled with high-throughput compatible MultiElectrod Arrays (MEAs), in collaboration with Axion BioSystems. These devices allow neurons and cancer cells co-culture with a control of cell density and homogeneity, and their functional and phenotypical analysis.
|CAPABILITIES||Functional Activity, Co-culture, hiPSC Derived Cell, Readouts|
|CHIP||R&D Nest MEA|
|CELL TYPE||Glutamatergic Neurons & Pediatric neuroblastoma|
|RESOURCES||Publications, Application Note, Application Protocol, Posters, Cells DataSheet|
|(FujiFilm CDI, BrainXell), Chip DataSheet|
|READINESS LEVEL||⑥ / ⑧ Readout done|