DuaLink
For 2 co-cultures & enhanced fluidic isolation
Explore
NeuroFluidics™ Line. NeuroFluidics™ MEA Line
9 Products with 4 architectures and 3 options.
Our NeuroFluidics™ line offers a variety of compartmentalized microfluidic devices and related applications.
Our NeuroFluidics™ MEA line achieves the fusion of the electrophysiology and compartmentalization. In collaboration with
Axion Biosystems we have developed MEA-capable high-throughput compartmentalized microfluidic devices.
DuaLink.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 2 co-cultures & fluidic isolation.
With the DuaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced fluidic isolation.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 4 up to 16 microfluidic chips per NeoBento
• Co-culture of different cell types
• Compartmentalization
• Fluidic isolation
• Discontinious connectivity by microchannels tunnels technology
.
With the DuaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced fluidic isolation.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 4 up to 16 microfluidic chips per NeoBento
• Co-culture of different cell types
• Compartmentalization
• Fluidic isolation
• Discontinious connectivity by microchannels tunnels technology
.
Readouts
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
Applications
DuaLink is specially designed to co-culture 2 cell types in channel 1 and 3 and allow fluidic isolation between the 3 channels.
This opens a wide array of applications :
In-vitro models:
• Innervated skin 2D
• Sensitive skin
• Chemotherapy Induced Peripheral Neuropathy (CIPN)
Applications:
• Axonal transport
• Skin nociception
• Itch
• Ageing
• Wound healing
• Toxicology
• Virology (viral transfection in one compartment only)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
• Neuromuscular junction
• Motor neuron diseases (Amyotrophic Lateral Sclerosis…)
This opens a wide array of applications :
In-vitro models:
• Innervated skin 2D
• Sensitive skin
• Chemotherapy Induced Peripheral Neuropathy (CIPN)
Applications:
• Axonal transport
• Skin nociception
• Itch
• Ageing
• Wound healing
• Toxicology
• Virology (viral transfection in one compartment only)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
• Neuromuscular junction
• Motor neuron diseases (Amyotrophic Lateral Sclerosis…)
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Resources
DuaLink Shift.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 2 co-cultures & synaptic isolation.
With the DuaLink Shift microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the creation of synaptic compartment.
• 3 compartments: 2 for cell culture & 1 for synaptic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Synapse isolation in the middle channel
• Asymmetrical shape with microchannels of different length (shorter length between the first and second channel than between the second and third channel)
• Discontinious connectivity by microchannels tunnels technology
.
With the DuaLink Shift microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the creation of synaptic compartment.
• 3 compartments: 2 for cell culture & 1 for synaptic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Synapse isolation in the middle channel
• Asymmetrical shape with microchannels of different length (shorter length between the first and second channel than between the second and third channel)
• Discontinious connectivity by microchannels tunnels technology
.
Readouts
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
Applications
DuaLink Shift is specially designed to isolate synaptic connections in channel 2 and allow fluidic isolation between the 3 channels.
This opens a wide array of applications :
Applications:
• Synaptic compartmentalization (pre-, post- and synaptic compartments)
• Synaptic transmission and localization
• Mitochondrial transport
• Microglial cells migration
• Neuroinflammation
• Huntington’s disorders (cortico-striatal)
• Study of the functional activity of neurons
.
This opens a wide array of applications :
Applications:
• Synaptic compartmentalization (pre-, post- and synaptic compartments)
• Synaptic transmission and localization
• Mitochondrial transport
• Microglial cells migration
• Neuroinflammation
• Huntington’s disorders (cortico-striatal)
• Study of the functional activity of neurons
.
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Resources
TriaLink.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 3 co-cultures & fluidic isolation.
With the TriaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of 3 different cell types
• Discontinuous connectivity by microchannels tunnels technology
.
With the TriaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of 3 different cell types
• Discontinuous connectivity by microchannels tunnels technology
.
Readouts
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
Applications
TriaLink is specially designed to co-culture 3 cell types in channel 1, 2 and 3, and allow fluidic isolation between the 3 channels.
This opens a wide array of applications :
Applications:
• Study of the functional activity of neurons
• Analysis of the functional influence of a non-neuronal cell population (astrocyte cells for example) on neurons
• Culture up to 3 different cell populations (neurons/glial cells or neurons/skin cells…)
• Cell migration/chemotaxis (microglia cells for example)
• Stress effect on skin cells (ROS…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
.
This opens a wide array of applications :
Applications:
• Study of the functional activity of neurons
• Analysis of the functional influence of a non-neuronal cell population (astrocyte cells for example) on neurons
• Culture up to 3 different cell populations (neurons/glial cells or neurons/skin cells…)
• Cell migration/chemotaxis (microglia cells for example)
• Stress effect on skin cells (ROS…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
.
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Resources
DuaLink MEA.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 2 isolated cultures connected via axons & functional activity recording.
With the DuaLink MEA microfluidic chip, the microchannels, NeoBento™ and electrophysiology technologies are combined in a single microfluidic chip, to recreate physiologicaly relevant 2 compartments of cell populations & monitor their functional activity :
• 3 compartments integrated on a custom Axion Biosystems MEA layer: 2 for cell culture & 1 for fluidic isolation
• 16 microfluidic chips per NeoBento™ MEA Pro with 672 electrodes
• 8 microfluidic chips per NeoBento™ MEA Edge with 336 electrodes
• Cell type electrophysology activity isolation per compartment
• Remote stimulation (compound or electrical)
.
With the DuaLink MEA microfluidic chip, the microchannels, NeoBento™ and electrophysiology technologies are combined in a single microfluidic chip, to recreate physiologicaly relevant 2 compartments of cell populations & monitor their functional activity :
• 3 compartments integrated on a custom Axion Biosystems MEA layer: 2 for cell culture & 1 for fluidic isolation
• 16 microfluidic chips per NeoBento™ MEA Pro with 672 electrodes
• 8 microfluidic chips per NeoBento™ MEA Edge with 336 electrodes
• Cell type electrophysology activity isolation per compartment
• Remote stimulation (compound or electrical)
.
Readouts
All our chips are in the NeoBento format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
Applications
DuaLink MEA is specially designed to co-culture 2 cell types in channel 1 and 3, and enable the recording of specific neuronal activities in each and accross channels.
In-vitro models:
• Nociceptive Pain
Applications:
• Study of the functional activity of neurons
• Analysis of the functional influence of a non-neuronal cell population on neurons
• Axonal transport
• Skin nociception
• Itch
• Ageing
• Wound healing
• Toxicology
• Virology (viral transfection in one compartment only)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
• Innervated skin
• Neuromuscular junction
• Motor neuron diseases (Amyotrophic Lateral Sclerosis…)
In-vitro models:
• Nociceptive Pain
Applications:
• Study of the functional activity of neurons
• Analysis of the functional influence of a non-neuronal cell population on neurons
• Axonal transport
• Skin nociception
• Itch
• Ageing
• Wound healing
• Toxicology
• Virology (viral transfection in one compartment only)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
• Innervated skin
• Neuromuscular junction
• Motor neuron diseases (Amyotrophic Lateral Sclerosis…)
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Electrophysiology: Combining our advanced organs-on-chip devices with Axion Biosystems’ Maestro MEA benchtop systems allows users to record and analyze each compartmentalized cell population independently, allowing them to better understand the relationships and effects at play.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment.
.
• Electrophysiology: Combining our advanced organs-on-chip devices with Axion Biosystems’ Maestro MEA benchtop systems allows users to record and analyze each compartmentalized cell population independently, allowing them to better understand the relationships and effects at play.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment.
.
Resources
DuaLink Shift MEA.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for synaptic isolation & functional activity recording.
With the DuaLink™ Shift MEA microfluidic chip, the microchannels, NeoBento™ and electrophysiology technologies are combined in a single microfluidic chip, to recreate a physiological synaptic compartmentalization & monitor their functional activity :
• 3 compartments integrated on a custom Axion Biosystems MEA layer: 2 for cell culture & 1 for synaptic isolation
• 16 microfluidic chips per NeoBento™ MEA Pro with 672 electrodes
• 8 microfluidic chips per NeoBento™ MEA Edge with 336 electrodes
• Asymmetrical shape with microchannels of different length
• Orientation of the network by preferentially allowing axons to develop from channel 3 to channel 1
• Synapses electrophysology activity isolation per compartment
With the DuaLink™ Shift MEA microfluidic chip, the microchannels, NeoBento™ and electrophysiology technologies are combined in a single microfluidic chip, to recreate a physiological synaptic compartmentalization & monitor their functional activity :
• 3 compartments integrated on a custom Axion Biosystems MEA layer: 2 for cell culture & 1 for synaptic isolation
• 16 microfluidic chips per NeoBento™ MEA Pro with 672 electrodes
• 8 microfluidic chips per NeoBento™ MEA Edge with 336 electrodes
• Asymmetrical shape with microchannels of different length
• Orientation of the network by preferentially allowing axons to develop from channel 3 to channel 1
• Synapses electrophysology activity isolation per compartment
Readouts
All our chips are in the NeoBento format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
Applications
DuaLink Shift MEA is specially designed to isolate synaptic connections in channel 2, and enable the recording of specific neuronal activities in each and accross channels.
This opens a wide array of applications :
Applications:
• Analysis of the functional influence of a non-neuronal cell population on synapse
• Synaptic compartmentalization (pre-, post- and synaptic compartments)
• Synaptic transmission and localization
• Mitochondrial transport
• Microglial cells migration
• Neuroinflammation
• Huntington’s disorders (cortico-striatal)
• Study of the functional activity of neurons
.
This opens a wide array of applications :
Applications:
• Analysis of the functional influence of a non-neuronal cell population on synapse
• Synaptic compartmentalization (pre-, post- and synaptic compartments)
• Synaptic transmission and localization
• Mitochondrial transport
• Microglial cells migration
• Neuroinflammation
• Huntington’s disorders (cortico-striatal)
• Study of the functional activity of neurons
.
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Electrophysiology: Combining our advanced organs-on-chip devices with Axion Biosystems’ Maestro MEA benchtop systems allows users to record and analyze each compartmentalized cell population independently, allowing them to better understand the relationships and effects at play.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment.
• Electrophysiology: Combining our advanced organs-on-chip devices with Axion Biosystems’ Maestro MEA benchtop systems allows users to record and analyze each compartmentalized cell population independently, allowing them to better understand the relationships and effects at play.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment.
Resources
TriaLink MEA.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 3 isolated cultures connected via axons & functional activity recording.
With the TriaLink™ Shift MEA microfluidic chip, the microchannels, NeoBento™ and electrophysiology technologies are combined in a single microfluidic chip, to recreate a to recreate physiologicaly relevant 3 compartments of cell populations & monitor their functional activity:
• 3 compartments integrated on a custom Axion Biosystems MEA layer: 3 for cell culture
• 16 microfluidic chips per NeoBento™ MEA Pro with 672 electrodes
• 8 microfluidic chips per NeoBento™ MEA Edge with 336 electrodes
• Cell type electrophysology activity isolation per compartment
• Remote stimulation (compound or electrical)
.
With the TriaLink™ Shift MEA microfluidic chip, the microchannels, NeoBento™ and electrophysiology technologies are combined in a single microfluidic chip, to recreate a to recreate physiologicaly relevant 3 compartments of cell populations & monitor their functional activity:
• 3 compartments integrated on a custom Axion Biosystems MEA layer: 3 for cell culture
• 16 microfluidic chips per NeoBento™ MEA Pro with 672 electrodes
• 8 microfluidic chips per NeoBento™ MEA Edge with 336 electrodes
• Cell type electrophysology activity isolation per compartment
• Remote stimulation (compound or electrical)
.
Readouts
All our chips are in the NeoBento format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
Applications
TriaLink MEA is specially designed to co-culture 3 cell types in channel 1, 2 and 3, and enable the recording of specific neuronal activities in each and accross channels.
This opens a wide array of applications :
Applications:
• Study of the functional activity of neurons
• Analysis of the functional influence of a non-neuronal cell population (astrocyte cells for example) on neurons
• Culture up to 3 different cell populations (neurons/glial cells or neurons/skin cells…)
• Cell migration/chemotaxis (microglia cells for example)
• Stress effect on skin cells (ROS…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
.
This opens a wide array of applications :
Applications:
• Study of the functional activity of neurons
• Analysis of the functional influence of a non-neuronal cell population (astrocyte cells for example) on neurons
• Culture up to 3 different cell populations (neurons/glial cells or neurons/skin cells…)
• Cell migration/chemotaxis (microglia cells for example)
• Stress effect on skin cells (ROS…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
.
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Electrophysiology: Combining our advanced organs-on-chip devices with Axion Biosystems’ Maestro MEA benchtop systems allows users to record and analyze each compartmentalized cell population independently, allowing them to better understand the relationships and effects at play.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment.
• Electrophysiology: Combining our advanced organs-on-chip devices with Axion Biosystems’ Maestro MEA benchtop systems allows users to record and analyze each compartmentalized cell population independently, allowing them to better understand the relationships and effects at play.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment.
Resources
DuaLink Ultra.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 2 co-cultures & enhanced axonal projection.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced axonal projection rate.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Co-culture of different cell types
• Enhanced axonal projection and time to results
• Continuous connectivity by microchannels grooves technology
.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced axonal projection rate.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Co-culture of different cell types
• Enhanced axonal projection and time to results
• Continuous connectivity by microchannels grooves technology
.
Readouts
All our chips are in the NeoBento format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
Applications
DuaLink Ultra is specially designed to co-culture 2 cell types in channel 1 and 3 and allow an enhanced axonal projection rate between channels.
This opens a wide array of applications :
In-vitro models:
• Peripheral Neuropathic Pain
Applications:
• Axonal transport
• Skin nociception
• Itch
• Ageing
• Wound healing
• Toxicology
• Virology (viral transfection in one compartment only)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
• Neuromuscular junction
• Motor neuron diseases (Amyotrophic Lateral Sclerosis…)
This opens a wide array of applications :
In-vitro models:
• Peripheral Neuropathic Pain
Applications:
• Axonal transport
• Skin nociception
• Itch
• Ageing
• Wound healing
• Toxicology
• Virology (viral transfection in one compartment only)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
• Neuromuscular junction
• Motor neuron diseases (Amyotrophic Lateral Sclerosis…)
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Resources
DuaLink Delta Ultra.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 2 co-cultures & enhanced growth kinetics.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced growth kinetics.
• 3 compartments: 1 for cell culture, 1 for fluidic isolation and 1 to monitor axonal growth
• 8 or 16 microfluidic chips per NeoBento™
• Enhanced growth kinetics
• Triangular shape with microchannels of different length
• Continuous connectivity by microchannels grooves technology
.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced growth kinetics.
• 3 compartments: 1 for cell culture, 1 for fluidic isolation and 1 to monitor axonal growth
• 8 or 16 microfluidic chips per NeoBento™
• Enhanced growth kinetics
• Triangular shape with microchannels of different length
• Continuous connectivity by microchannels grooves technology
.
Readouts
All our chips are in the NeoBento format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
Applications
DuaLink Delta Ultra is specifically designed to monitor growth kinetics between channels 2 and 3 and allow an enhanced axonal projection rate between channels.
This opens a wide array of applications :
In-vitro models:
• Motor Nerve Injury
• Sensory Nerve Injury
Applications:
• Growth kinetics quantification
• Axonal regeneration visualization and quantification
• Co-culture (in the same compartment, like Schwann cells/sensory neurons or astrocyte cells/motor neurons…)
• Embryology
• Axotomy
• Peripherical pain
• Motor neuron diseases (Amyotrophic Lateral Sclerosis, Spinal muscular atrophy…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
This opens a wide array of applications :
In-vitro models:
• Motor Nerve Injury
• Sensory Nerve Injury
Applications:
• Growth kinetics quantification
• Axonal regeneration visualization and quantification
• Co-culture (in the same compartment, like Schwann cells/sensory neurons or astrocyte cells/motor neurons…)
• Embryology
• Axotomy
• Peripherical pain
• Motor neuron diseases (Amyotrophic Lateral Sclerosis, Spinal muscular atrophy…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
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Resources
TriaLink Ultra.
Description
Readouts
Applications
Technologies
Resources
Description
Specially designed for 2 co-cultures & enhanced growth kinetics.
With the TiaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unmatched user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of different cell types
• Continuous connectivity by microchannels grooves technology
.
With the TiaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unmatched user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of different cell types
• Continuous connectivity by microchannels grooves technology
.
Readouts
All our chips are in the NeoBento format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
• Human cells
• Rodent cells
• Immunofluorescence
• Live Dead Assays
• Live staining
• Liquid chromatography
• Mass Spectoscopy
• Lysis cells/supernatant analysis
• ELISA
• Calcium Imaging
.
Applications
TriaLink Ultra is specially designed to co-culture 3 cell types in channel 1, 2 and 3, and allow an enhanced axonal projection rate between channels.
This opens a wide array of applications :
Applications:
• Culture up to 3 different cell populations (neurons/glial cells or neurons/skin cells…)
• Cell migration/chemotaxis (microglia cells for example)
• Stress effect on skin cells (ROS…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
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This opens a wide array of applications :
Applications:
• Culture up to 3 different cell populations (neurons/glial cells or neurons/skin cells…)
• Cell migration/chemotaxis (microglia cells for example)
• Stress effect on skin cells (ROS…)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
.
Technologies
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
Resources