Specially designed to become proficient on electrophysiology recording, the MEA-recording training kit is composed of:
• 2 QuarterBentos of DuaLink MEA
• 1 NeoBento EDGE frame with 2 plugs
• UpLink utility software
• In-depth online training on electrophysiology recording
What do you need to use it?
• Maestro EDGE or PRO, powered by
Axion BioSystems
• UpLink downloadable from
NETRI Support Page
• Standard equipments (biological safety cabinet, micropipettes etc…)
• Standard consumables (Ethanol 70%, distilled water etc…)
To see all equipment and consumables required, please contact our
support services.
All our chips are in the NeoBento™ MEA format (standard 96-well SBS plate format) and thus offer a variety of handling readouts.
Electrophysiology (Using AxIS and
NETRI’s Uplink utility software)
• Axion MEA metrics (per channel / µchannel)
• Axion MEA Network Metrics (per channel)
• Individual Axion Electrode Metrics
• Compartimentalized Rasterplots
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectroscopy
In-vitro models:
• Nociceptive Pain
• Innervated skin 2D
Applications
• Study of the functional activity of neurons
• Analysis of the functional influence of a non-neuronal cell population on neurons
• Axonal transport
• Skin nociception
• Itch
• Ageing
• Wound healing
• Toxicology
• Virology (viral transfection in one compartment only)
• Neuroinflammation (Multiple sclerosis, Cerebral tumors…)
• Innervated skin
• Neuromuscular junction
• Motor neuron diseases (Amyotrophic Lateral Sclerosis…)
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Electrophysiology: Combining our advanced organs-on-chip devices with Axion Biosystems’ Maestro MEA benchtop systems allows users to record and analyze each compartmentalized cell population independently, allowing them to better understand the relationships and effects at play.
• Microchannel tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.