DuaLink
For 2 co-cultures & enhanced fluidic isolation
Explore
NeuroFluidics™ Line.
6 Products with 4 architectures and 2 options.
Our NeuroFluidics™ line offers a variety of microfluidic devices and related applications, with its 4 architectures and 2 options.
DuaLink.
Specially designed for 2 co-cultures & fluidic isolation.
With the DuaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced fluidic isolation.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 4 up to 16 microfluidic chips per NeoBento
• Co-culture of different cell types
• Compartmentalization
• Fluidic isolation
•Discontinious connectivity by microchannels tunnels technology
.
With the DuaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced fluidic isolation.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 4 up to 16 microfluidic chips per NeoBento
• Co-culture of different cell types
• Compartmentalization
• Fluidic isolation
•Discontinious connectivity by microchannels tunnels technology
.
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
DuaLink is specially designed to co-culture 2 cell types in channel 1 and 3 and allow fluidic isolation between the 3 channels.
In-vitro models
• Innervated skin 2D
• Sensitive skin
Indications
• Neurological Troubles (AD, PD, ALS, MS)
• Skin nociception
Field
• Toxicology
• Virology
• Neuroinflammation
• Itch
• Ageing
Capabilities
• Axonal transport
• Co-culture & compartmentalization
In-vitro models
• Innervated skin 2D
• Sensitive skin
Indications
• Neurological Troubles (AD, PD, ALS, MS)
• Skin nociception
Field
• Toxicology
• Virology
• Neuroinflammation
• Itch
• Ageing
Capabilities
• Axonal transport
• Co-culture & compartmentalization
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannels tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannels tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Publications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
DuaLink Shift.
Specially designed for 2 co-cultures & synaptic isolation.
With the DuaLink Shift microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the creation of synaptic compartment.
• 3 compartments: 2 for cell culture & 1 for synaptic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Synapse isolation in the middle channel
• Asymmetrical shape with microchannels of different length (shorter length between the first and second channel than between the second and third channel)
• Discontinious connectivity by microchannels tunnels technology
.
With the DuaLink Shift microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the creation of synaptic compartment.
• 3 compartments: 2 for cell culture & 1 for synaptic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Synapse isolation in the middle channel
• Asymmetrical shape with microchannels of different length (shorter length between the first and second channel than between the second and third channel)
• Discontinious connectivity by microchannels tunnels technology
.
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
DuaLink Shift is specially designed to isolate synaptic connections in channel 2 and allow fluidic isolation between the 3 channels.
Indications
• Huntington Disease
• Alzheimer Disease – Glutamate
• Parkinson Disease – αsyn
Field
• Neuroinflammation
• Neuro-immunology
• Synaptic Transmission
Capabilities
• Synaptic isolation
• Co-culture & compartmentalization
• Axonal transport
.
Indications
• Huntington Disease
• Alzheimer Disease – Glutamate
• Parkinson Disease – αsyn
Field
• Neuroinflammation
• Neuro-immunology
• Synaptic Transmission
Capabilities
• Synaptic isolation
• Co-culture & compartmentalization
• Axonal transport
.
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannels tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannels tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Publications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
TriaLink.
Specially designed for 3 co-cultures & fluidic isolation.
With the TriaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of 3 different cell types
• Discontinuous connectivity by microchannels tunnels technology
.
With the TriaLink microfluidic chip, microchannels tunnels and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of 3 different cell types
• Discontinuous connectivity by microchannels tunnels technology
.
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
TriaLink is specially designed to co-culture 3 cell types in channel 1, 2 and 3, and allow fluidic isolation between the 3 channels.
Indications
• Multiple sclerosis
• Cerebral tumors
Field
• Neuroinflammation
• Gut-Brain-Axis
Capabilities
• Co-culture & compartmentalization
• Axonal transport
.
Indications
• Multiple sclerosis
• Cerebral tumors
Field
• Neuroinflammation
• Gut-Brain-Axis
Capabilities
• Co-culture & compartmentalization
• Axonal transport
.
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannels tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannels tunnels: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced fluidic isolation and discontinuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Publications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
DuaLink Ultra.
Specially designed for 2 co-cultures & enhanced axonal projection.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced axonal projection rate.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Co-culture of different cell types
• Enhanced axonal projection and time to results
• Continuous connectivity by microchannels grooves technology
.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced axonal projection rate.
• 3 compartments : 2 for cell culture & 1 for fluidic isolation
• 8 or 16 microfluidic chips per NeoBento™
• Co-culture of different cell types
• Enhanced axonal projection and time to results
• Continuous connectivity by microchannels grooves technology
.
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
DuaLink Ultra is specially designed to co-culture 2 cell types in channel 1 and 3 and allow an enhanced axonal projection rate between channels.
In-vitro models
• Peripheral Neuropathic Pain
Indications
• Neurological Troubles (AD, PD, ALS, MS)
• Skin nociception
Field
• Toxicology
• Virology
• Neuroinflammation
• Itch
• Ageing
Capabilities
• Axonal transport
• Co-culture & compartmentalization
.
In-vitro models
• Peripheral Neuropathic Pain
Indications
• Neurological Troubles (AD, PD, ALS, MS)
• Skin nociception
Field
• Toxicology
• Virology
• Neuroinflammation
• Itch
• Ageing
Capabilities
• Axonal transport
• Co-culture & compartmentalization
.
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Publications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
DuaLink Delta Ultra.
Specially designed for 2 co-cultures & enhanced growth kinetics.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced growth kinetics.
• 3 compartments: 1 for cell culture, 1 for fluidic isolation and 1 to monitor axonal growth
• 8 or 16 microfluidic chips per NeoBento™
• Enhanced growth kinetics
• Triangular shape with microchannels of different length
• Continuous connectivity by microchannels grooves technology
.
With the DuaLink Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unparalleled user experience combined with an enhanced growth kinetics.
• 3 compartments: 1 for cell culture, 1 for fluidic isolation and 1 to monitor axonal growth
• 8 or 16 microfluidic chips per NeoBento™
• Enhanced growth kinetics
• Triangular shape with microchannels of different length
• Continuous connectivity by microchannels grooves technology
.
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
DuaLink Delta Ultra is specifically designed to monitor growth kinetics between channels 2 and 3 and allow an enhanced axonal projection rate between channels.
In-vitro models
• Motor Nerve Injury
• Sensory Nerve Injury
Indications
• Alzheimer Disease – Tau
• Spinal muscular atrophy
Field
• Neuroinflammation
• Neurodevelopment
• Regenerative medicine
Capabilities
• Axotomy
• Growth kinetics quantification
• Co-culture & compartmentalization
• Axonal transport
In-vitro models
• Motor Nerve Injury
• Sensory Nerve Injury
Indications
• Alzheimer Disease – Tau
• Spinal muscular atrophy
Field
• Neuroinflammation
• Neurodevelopment
• Regenerative medicine
Capabilities
• Axotomy
• Growth kinetics quantification
• Co-culture & compartmentalization
• Axonal transport
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Publications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
TriaLink Ultra.
Specially designed for 2 co-cultures & enhanced growth kinetics.
With the Link Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unmatched user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of different cell types
• Continuous connectivity by microchannels grooves technology
.
With the Link Ultra microfluidic chip, the microchannels grooves and HT format NeoBento™ technologies are combined in a single chip to provid an unmatched user experience combined with the ability to culture up to 3 different cell types.
• 3 compartments for independant 3 different cell type cultures
• 8 or 16 microfluidic chips per NeoBento™
• Up to tri-culture of different cell types
• Continuous connectivity by microchannels grooves technology
.
All our chips are in the NeoBento™ format (standard 96-well SBS plate format) and thus offer a variety of handling readouts for your different needs.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
Imaging
• Immunofluorescence
• Calcium Imaging
• Live staining
• Live Dead Assays
Biochimic analysis
• Lysis cells analysis
• Supernatant analysis
• ELISA
• Liquid chromatography
• Mass Spectoscopy
.
TriaLink Ultra is specially designed to co-culture 3 cell types in channel 1, 2 and 3, and allow an enhanced axonal projection rate between channels.
Indications
• Multiple sclerosis
• Cerebral tumors
Field
• Neuroinflammation
• Gut-Brain-Axis
Capabilities
• Co-culture & compartmentalization
• Axonal transport
.
Indications
• Multiple sclerosis
• Cerebral tumors
Field
• Neuroinflammation
• Gut-Brain-Axis
Capabilities
• Co-culture & compartmentalization
• Axonal transport
.
Our aim is to translate physiological behaviors by integrating our technologies within one chip.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
• Microchannel grooves: Due to their micrometric measurements, only cell extensions can grow within the microchannels, leaving the cell bodies within the compartments themselves, that allow an enhanced axonal projection rate and continuous connectivity between compartments.
• NeoBento™ HT Format: The NeoBento is our versatile container which is in the standard 96-well microplate format, compatible with standard liquid handling and imaging equipment, and does not require expensive equipment. The NeoBento™ makes NETRI’s microfluidic devices as versatile and easy to handle as a typical 96-well plate.
.
Publications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks
Electrokinetic confinement of axonal growth for dynamically configurable neural networks
Microfluidic neurite guidance to study structure-function relationships in topologically complex population-based neural networks
Microfluidic Devices Protocols
NeuroFluidics™ – DuaLink - DuaLink MEA
Cells Types Protocols
Sensory Neurons – Axol Bioscience
Application Notes
Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons
Posters
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications