What are Membranes?

Membrane technology consists of a solid matrix with defined holes or pores which have diameters ranging from less than 2 nm to more than 20 μm depending on the application (neuron extensions, molecules, proteins etc.). Generally used in cell biology for studying cell migration, cell-cell signaling and cell filtration, in NETRI’s microfluidic chips, they could be used for all these applications coupled with avantages of the microfluidic.

What are the benefits ?

  • Mimic physiological barriers
  • Control exchanges and communication between cell populations
  • Use smaller volume
  • Manipulate more easily

NETRI’s porous membrane and microfluidic chip

  • Multi-compartmentalized and connected barriers: several compartmentalized and connected barriers can be interconnected to actually recreate cell-cell interactions, tissue-neuron interaction and study the signaling pathway
  • Physiological separation: 2 compartments containing different cell populations can be separated while interacting and perfectly controlling the culture medium
  • Diffusion: nutrients or molecules from underneath the cell culture can diffuse, thus allowing a total perfusion and control of the multilayer cell culture like skin cells