Abstract Microfluidic neuro-engineering design rules have been widely explored to create in vitro neural networks with the objective to replicate physiologically relevant structures of the brain. Several neurofluidic strategies have been reported to study the connectivity of neurons, either within a population or between two separated populations, through the control of the directionality of their […]
Abstract Compartmentalized microfluidic chips have demonstrated tremendous potential to create in vitro minimalistic environments for the reproduction of the neural circuitry of the brain. Although the protocol for seeding neural soma in these devices is well known and has been widely used in myriad studies, the accurate control of the number of neurites passing through […]
NETRI offers free samples for research teams that are working on SRAS-CoV-2 interactions with the central/peripheral nervous system. Neurofluidic™ chips allow fluid isolation of neural types to study the spread of the virus through synaptic chambers. Contact us ASAP! Coronavirus humains respiratoires neuro-invasifs et neurotropes : agents neurovirulents potentiels. Marc Desforges, Alain Le Coupanec, Élodie Brison, […]
Press ReleaseMarch 25th, 2020 Breackthrough unlocks progress in brain-on-a-chip technology Massively accelerated image processing supports development of novel treatments for neurological conditions Lyon, March 25, 2020 – Cambridge Consultants and Neuro Engineering Technologies Research Institute (NETRI) announce a breakthrough in precision imaging of brain activity. Working with NETRI’s brain-on-a-chip technology and lensless imaging approach that detects […]
Abstract Proper brain function relies on the precise arrangement and flow of information between diverse neural subtypes. Developing improved human cell-based models which faithfully mimic biologically relevant connectivity patterns may improve drug screening efforts given the limited success of animal models to predict safety and efficacy of therapeutics in human clinical trials. To address this […]
In vitro modeling of human brain connectomes is key to explore the structure-function relationship of the centralnervous system. The comprehension of this intricate relationship will serve to better study the pathological mechanismsof neurodegeneration, and hence to perform improved drug screenings for complex neurological disorders, such asAlzheimer’s and Parkinson’s diseases. However, currently used in vitro modeling […]