Parvatam, S., Pamies, D., Pistollato, F., Beken, S., Mariappan, I., Roth, A., … & Coecke, S. (2023). Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems. Stem Cell Reports. https://doi.org/10.1016/j.stemcr.2023.11.008

Gabriel-Segard, T.; Rontard, J.; Miny, L.; Dubuisson, L.; Batut, A.; Debis, D.; Gleyzes, M.; François, F.; Larramendy, F.; Soriano, A.; et al. (2023). Proof-of-Concept Human Organ-on-Chip Study: First Step of Platform to Assess Neuro-Immunological Communication Involved in Inflammatory Bowel Diseases. Int. J. Mol. Sci., 24, 10568. https://doi.org/10.3390/ ijms241310568

Rontard J, Maisonneuve BGC, Honegger T. (2023). Expanding human-based predictive models capabilities using organs-on-chip: A standardized framework to transfer and co-culture human iPSCs into microfluidic devices. Arch Pharm Pharma Sci. ; 7: 017-021. https://doi.org/10.29328/journal.apps.1001039

Castiglione, H., Vigneron, P. A., Baquerre, C., Yates, F., Rontard, J., & Honegger, T. (2022). Human Brain Organoids-on-Chip: Advances, Challenges, and Perspectives for Preclinical Applications. Pharmaceutics, 14(11), 2301. https://doi.org/10.3390/pharmaceutics14112301

Maisonneuve, B. G. C., Libralesso, L., Miny, L., Batut, A., Rontard, J., Gleyzes, M., … & Honegger, T. (2022). Deposition chamber technology as building blocks for a standardized brain-on-chip framework. Microsystems & Nanoengineering, 8(1), 86. https://doi.org/10.1038/s41378-022-00406-x

Miny, L., Maisonneuve, B. G., Quadrio, I., & Honegger, T. (2022). Modeling neurodegenerative diseases using in vitro compartmentalized microfluidic devices. Frontiers in Bioengineering and Biotechnology, 10, 919646. https://doi.org/10.3389/fbioe.2022.919646

Guichard, A., Remoué, N., & Honegger, T. (2022). In vitro sensitive skin models: review of the standard methods and introduction to a new disruptive technology. Cosmetics, 9(4), 67. https://doi.org/10.3390/cosmetics9040067

Fuchs, Q., Batut, A., Gleyzes, M., Rontard, J., Miny, L., Libralato, M., Vieira, J., Debis, D., Larramendy, F., Honegger, T., Messe, M., Pierrevelcin, M., Lhermitte, B., Dontenwill, M., Entz-Werlé, N. (2021). Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions. J. Vis. Exp. (177), e62748, https://doi.org/10.3791/62748

Maisonneuve, B. G. C., Vieira, J., Larramendy, F., & Honegger, T. (2021). Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks. BioRxiv, 2021-03. https://doi.org/10.1101/2021.03.05.434080

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NETRI, Who we are

NETRI Pain & Injury

NETRI Dermo-cosmetics

NETRI Readout diversity

NETRI NeuroFluidics Line

NETRI NeoBento HT Format

NETRI hiPSC culture

NETRI Electrophysiology

[2024] Characterizing sensory neurons as universal bio-digital sensors to explore PNS applications

[2024] Traumatic Nerve Injury Platform

[2023] Chemotherapy-Induced Peripheral Neuropathy-On-Chip Model : Utilizing the strength of compartmentalization

[2023] Surface tension-based cell seeding in NETRI microfluidic devices

[2023] Compartimentalized culture of primary or hiPSC-derived neurons using an MEA-capable high-throughput organs-on-chip platform

[2022] Synaptic transmission investigation using asymmetric shape microfluidic device DuaLink Shift

[2022] The DuaLink Chips how to improve reproducibility in compartmentalized co-cultures

[2022] Innovative microfluidic device for in vitro 3D cell culture

[2021] High Thoughput microfluidic device for long-term culture and functional activity recording of organoids and explants

[2021] Evaluation of amyloid beta oligomers (AβO) effects on functional network integrity of rodent hippocampal neurons

[2022] Methodology for quantify cell viability after acute exposure of amyloid beta oligomers on human neurons

[2021] Simple quantitative method of neurite length measurements in triangular microfluidic device

Neurosciences 2024

Advancing Neuromuscular Junction Modeling with Compartmentalized Microfluidic Platforms Coupled with MEA Functional Analysis

Development of a Brain Organoid-on-Chip Platform for Neurotoxicity Testing

Digital Signature Library: using neurons as universal bio-digital sensors

EUROoCS 2024

Translational brain-on-a-chip models for Alzheimer’s disease drug discovery

Human Brain Organoid-on-Chip platform to improve organoid reproducibility and scalability for pharmaceutical studies

Compartimentalized MEA Pain(s)-on-chip platform

MPS World Summit 2024

Compartimentalized MEA Pain(s)-on-chip platform

Human Brain Organoid-on-Chip platform to improve organoid reproducibility and scalability for pharmaceutical studies

Translational brain-on-a-chip models for Alzheimer’s disease drug discovery

AD/PD 2024

Advancing Alzheimer’s disease models for target validation and drug discovery

World of organoids 2024

Prediction algorithm for neurotoxicity evaluation based on brain organoid-on-chip

A new human brain organoid-on-chip model meeting biological and industrial requirements of neurological preclinical studies

SfN 2023

Towards new relevant Alzheimer’s disease models for target validation and drug testing

A new human brain organoid-on-chip model meeting biological and industrial requirements of neurological precilinical studies

Translational platforms of injury & pain-on-chip

Automated organs-on-chip platform to reduce intra-laboratory cell culture variability

MPS World Summit 2023

Automated Organs-on-chip platform to reduce intra-laboratory cell culture variability

A new versatile 3D Organs-on-chip model allowing air-liquid interface, blood-tissue barrier recreation and multicompartment connection

Functional skin-on-chip: a relevant in-vitro platform to replace animal models in drug and cosmetic development

Translational model of nerve injury-on-chip

PNS 2023

Translational model of nerve injury-on-chip

NeuroFrance 2023

Translational model of nerve injury-on-chip

A new versatile 3D Organs-on-chip model allowing air-liquid interface, blood-tissue barrier recreation and multicompartment connection

SfN 2022

NeoBento High Throughput Format

Pain-on-Chip – Motor nerve injury

FENS 2022

An Organ on chip platform to evaluate neuro immune signal transmission using human cells

Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury

Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications

EUROoCS 2022

Deposition chamber technology as building blocks for a standardized brain on chip framework

Development of an innervated skin-on-a-chip

Human Brain-Organoids-on-ChipAdvanced microfluidic device for reproducible organoids culture

Organs-on-Chip high throughput platform for pharmaceutical screening

The DuaLink chips Improved fluidic isolation in microfluidic devices designed for neurons culture

MPS World Summit 2022
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons

Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injuryStandardization criteria of hiPSC-derived neurons for Brain-on-Chip applications

Human Brain-Organoids-on-Chip Advanced microfluidic device for reproducible organoids culture

SLAS Europe 2022
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury

Organs-on-Chip high throughput platform for pharmaceutical screening

Microphysiological Systems Workshop

Human Brain-Organoids-on-Chip: Advanced microfluidic device for reproducible organoids culture

SLAS International 2022

Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons

MPS World Summit 2021
Deposition chamber technology as building blocks for a standardized brain-on-chip framework

Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications

Neurosciences 2021

Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury

FSSCR 2021
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury

Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications

MicroTas 2021
Co-culture model of glutamatergic neurons and pediatric high-grade glioma cell lines in microfluidic devices to evaluate electrophysiological impact

Neurite growth kinetics regulation through hydrostatic pressure in a novel triangle-shaped neurofluidic system.

EUROoCS 2021
High throughput standardised microfluidic platform for internalization and axonal transport explorations of a preclinical neurological compound

Co-culture model of glutamatergic neurons and pediatric high-grade glioma cell lines in microfluidic devices to evaluate electrophysiological impact

Neurite growth kinetics regulation through hydrostatic pressure in a novel triangle-shaped neurofluidic system.

Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications

Neurofrance 2021
Co-culture model of glutamatergic neurons and pediatric high-grade glioma cell lines in microfluidic devices to evaluate electrophysiological impact

High throughput standardised microfluidic platform for internalization and axonal transport explorations of a preclinical neurological compound

Neurite growth kinetics regulation through hydrostatic pressure in a novel triangle-shaped neurofluidic system

ISSCR 2021
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury