Parvatam, S., Pamies, D., Pistollato, F., Beken, S., Mariappan, I., Roth, A., … & Coecke, S. (2023). Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems. Stem Cell Reports. https://doi.org/10.1016/j.stemcr.2023.11.008
Gabriel-Segard, T.; Rontard, J.; Miny, L.; Dubuisson, L.; Batut, A.; Debis, D.; Gleyzes, M.; François, F.; Larramendy, F.; Soriano, A.; et al. (2023). Proof-of-Concept Human Organ-on-Chip Study: First Step of Platform to Assess Neuro-Immunological Communication Involved in Inflammatory Bowel Diseases. Int. J. Mol. Sci., 24, 10568. https://doi.org/10.3390/ ijms241310568
Rontard J, Maisonneuve BGC, Honegger T. (2023). Expanding human-based predictive models capabilities using organs-on-chip: A standardized framework to transfer and co-culture human iPSCs into microfluidic devices. Arch Pharm Pharma Sci. ; 7: 017-021. https://doi.org/10.29328/journal.apps.1001039
Castiglione, H., Vigneron, P. A., Baquerre, C., Yates, F., Rontard, J., & Honegger, T. (2022). Human Brain Organoids-on-Chip: Advances, Challenges, and Perspectives for Preclinical Applications. Pharmaceutics, 14(11), 2301. https://doi.org/10.3390/pharmaceutics14112301
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[2024] Characterizing sensory neurons as universal bio-digital sensors to explore PNS applications
[2024] Traumatic Nerve Injury Platform
[2023] Surface tension-based cell seeding in NETRI microfluidic devices
[2022] Synaptic transmission investigation using asymmetric shape microfluidic device DuaLink Shift
[2022] The DuaLink Chips how to improve reproducibility in compartmentalized co-cultures
[2022] Innovative microfluidic device for in vitro 3D cell culture
NeuroFluidics™ – DuaLink Technical Specification
NeuroFluidics™ – DuaLink Delta Ultra Technical Specification
NeuroFluidics™ – DuaLink MEA Technical Specification
NeuroFluidics™ – DuaLink Shift Technical Specification
NeuroFluidics™ – DuaLink Shift MEA Technical-Specification
NeuroFluidics™ – DuaLink Ultra Technical Specification
NeuroFluidics™ – TriaLink Technical Specification
NeuroFluidics™ – TriaLink MEA Technical Specification
NeuroFluidics™ – TriaLink Ultra Technical Specification
GABAergic Neurons BrainXell
GABAergic Neurons FCDI
Glutamatergic Neurons BrainXell
Motor Neurons BrainXell
Motor Neurons FCDI
Dopaminergic Neurons FCDI
NeuroFluidics™ – DuaLink Delta Ultra
NeuroFluidics™ – DuaLink MEA
NeuroFluidics™ – DuaLink Shift
NeuroFluidics™ – DuaLink Ultra
NeuroFluidics™ – DuaLink
NeuroFluidics™ – TriaLink Ultra
NeuroFluidics™ – TriaLink
BrainXell, Cortical GABAergic Neurons, MEA assay
BrainXell, Cortical Glutamatergic Neurons, MEA assay
BrainXell, Cortical Glutamatergic Neurons
FCDI, iCell Motor Neurons
AXOL, axoCells™ sensory neurons
Compartimentalized MEA Pain(s)-on-chip platform
Human Brain Organoid-on-Chip platform to improve organoid reproducibility and scalability for pharmaceutical studies
Translational brain-on-a-chip models for Alzheimer’s disease drug discovery
AD/PD 2024
Advancing Alzheimer’s disease models for target validation and drug discovery
World of organoids 2024
Prediction algorithm for neurotoxicity evaluation based on brain organoid-on-chip
A new human brain organoid-on-chip model meeting biological and industrial requirements of neurological preclinical studies
SfN 2023
Towards new relevant Alzheimer’s disease models for target validation and drug testing
A new human brain organoid-on-chip model meeting biological and industrial requirements of neurological precilinical studies
Translational platforms of injury & pain-on-chip
Automated organs-on-chip platform to reduce intra-laboratory cell culture variability
MPS World Summit 2023
Automated Organs-on-chip platform to reduce intra-laboratory cell culture variability
A new versatile 3D Organs-on-chip model allowing air-liquid interface, blood-tissue barrier recreation and multicompartment connection
Functional skin-on-chip: a relevant in-vitro platform to replace animal models in drug and cosmetic development
Translational model of nerve injury-on-chip
PNS 2023
Translational model of nerve injury-on-chip
NeuroFrance 2023
Translational model of nerve injury-on-chip
A new versatile 3D Organs-on-chip model allowing air-liquid interface, blood-tissue barrier recreation and multicompartment connection
SfN 2022
NeoBento High Throughput Format
Pain-on-Chip – Motor nerve injury
FENS 2022
An Organ on chip platform to evaluate neuro immune signal transmission using human cells
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
EUROoCS 2022
Deposition chamber technology as building blocks for a standardized brain on chip framework
Development of an innervated skin-on-a-chip
Human Brain-Organoids-on-ChipAdvanced microfluidic device for reproducible organoids culture
Organs-on-Chip high throughput platform for pharmaceutical screening
The DuaLink chips Improved fluidic isolation in microfluidic devices designed for neurons culture
MPS World Summit 2022
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injuryStandardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Human Brain-Organoids-on-Chip Advanced microfluidic device for reproducible organoids culture
SLAS Europe 2022 Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Organs-on-Chip high throughput platform for pharmaceutical screening
Microphysiological Systems Workshop
Human Brain-Organoids-on-Chip: Advanced microfluidic device for reproducible organoids culture
SLAS International 2022
Modeling the human Brain-on-Chip with human iPSC-derived Glutamatergic neurons
MPS World Summit 2021
Deposition chamber technology as building blocks for a standardized brain-on-chip framework
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Neurosciences 2021
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
FSSCR 2021
Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
MicroTas 2021
Co-culture model of glutamatergic neurons and pediatric high-grade glioma cell lines in microfluidic devices to evaluate electrophysiological impact
Neurite growth kinetics regulation through hydrostatic pressure in a novel triangle-shaped neurofluidic system.
EUROoCS 2021
High throughput standardised microfluidic platform for internalization and axonal transport explorations of a preclinical neurological compound
Co-culture model of glutamatergic neurons and pediatric high-grade glioma cell lines in microfluidic devices to evaluate electrophysiological impact
Neurite growth kinetics regulation through hydrostatic pressure in a novel triangle-shaped neurofluidic system.
Standardization criteria of hiPSC-derived neurons for Brain-on-Chip applications
Neurofrance 2021
Co-culture model of glutamatergic neurons and pediatric high-grade glioma cell lines in microfluidic devices to evaluate electrophysiological impact
High throughput standardised microfluidic platform for internalization and axonal transport explorations of a preclinical neurological compound
Neurite growth kinetics regulation through hydrostatic pressure in a novel triangle-shaped neurofluidic system
ISSCR 2021 Microfluidic high-throughput screening platform to screen pre-clinical stage compound effects on neurite outgrowth of human Motor Neurons post-injury
